Deanna Angello is a results-driven life sciences executive who has spent more than two decades turning breakthrough science into market-shaping businesses. Across senior commercial roles at Pfizer, Genentech/Roche, Kite Pharma/Gilead, and Johnson & Johnson, she has launched and scaled seven blockbuster therapies, safeguarded a $10 billion franchise from biosimilar erosion, and driven more than $7 billion in incremental revenue. Whether architecting first-in-class launches, leading transformations, or evolving operating models, Deanna is known for marrying strategy and data rigor with entrepreneurial speed to unlock sustainable growth.
Today, she brings that discipline to early-stage innovators as an advisor, board member, and angel investor. Deanna is currently Board Advisor to ixlayer and SereNeuro Therapeutics, and Venture Partner at LongeVC. She works hands-on with founders through Springboard Enterprises, IGNITE, Creative Destruction Lab, and mentors several startup CEOs across the healthcare continuum. She also invests in healthy-aging technologies and products via Portfolia’s Active Aging & Longevity Fund.
Deanna holds an MBA in Strategic Management & Finance from Indiana University’s Kelley School of Business and a BS in Psychology from the University of Pittsburgh. An endurance athlete and committed advocate, she has summited Mt. Everest’s iconic trails, completed multiple marathons and triathlons, and raised more than $75,000 for frontotemporal dementia (FTD) and cancer research.
Relentless about making healthcare more human, Deanna blends Fortune 50 discipline with startup velocity to create value for patients, investors, and teams—at every stage of the company journey.